Some basic mechanisms of hunger and satiety

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Neural Control of Hunger, Appetite, and Satiety **

Hunger, appetite, and satiety are often regarded as problems in the physiology of digestion. In recent years, however, they have been studied more and more commonly as functions of the brain. This latter point of view, i.e., neurophysiology, is used in the paper which follows, and the regulation of food intake is here described in terms of mechanisms and reactions that characterize the nervous ...

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UNDERSTANDING THE PHYSIOLOGICAL controls of eating and developing effective pharmacological tools to reduce eating has never been more important. The modern world faces an unprecedented obesity epidemic, and the current treatment strategies are rather unsuccessful. One possible solution may be a combination or cocktail therapy. Obesity control research has been more focused on “long-term” adipo...

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Hunger and Satiety Gauge Reward Sensitivity

Many of the neurocircuits and hormones known to underlie the sensations of hunger and satiety also substantially alter the activity of the dopaminergic reward system. Much interest lies in the ways that hunger, satiety, and reward tie together, as the epidemic of obesity seems tied to the recent development and mass availability of highly palatable foods. In this review, we will first discuss t...

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Hunger and Satiety Mechanisms and Their Potential Exploitation in the Regulation of Food Intake.

Effective strategies to combat recent rises in obesity levels are limited. The accumulation of excess body fat results when energy intake exceeds that expended. Energy balance is controlled by hypothalamic responses, but these can be overridden by hedonic/reward brain systems. This override, combined with unprecedented availability of cheap, energy-dense, palatable foods, may partly explain the...

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ژورنال

عنوان ژورنال: Proceedings of the Nutrition Society

سال: 1962

ISSN: 0029-6651,1475-2719

DOI: 10.1079/pns19620012